Anti-CERK antibody,Abcam,AB155061

Host

Rabbit

Reactivity

Human

Application

IHC-P, WB

Platform ID

BAB572625681

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-CERK antibody
Cat. No.AB155061
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, WB
ClonalityPolyclonal
Concentration1.38 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CERK aa 50-350. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate (PubMed : 11956206, PubMed : 16269826, PubMed : 19168031). Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines (PubMed : 11956206, PubMed : 16269826, PubMed : 19168031). Shows a greater preference for D-erythro isomer of ceramides (PubMed : 16269826). Binds phosphoinositides (PubMed : 19168031). See full target information CERK

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