Anti-CGRP antibody,Abcam,AB195387

Host

Sheep

Reactivity

Rat

Application

IHC-P

Platform ID

BAB073275369

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CGRP antibody
Cat. No.AB195387
HostSheep
IsotypeIgG
ReactivityRat
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityPrecipitation Ammonium Sulphate
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex. See full target information Calca

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