Anti-CHD3 antibody [EPNCIR110A],Abcam,AB109195

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . Collaborations This antibody was developed as part of a collaboration between Epitomics, the National Cancer Institute's Center for Cancer Research and the lab of Gordon Hager. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Rat, Human

Application

WB, ICC/IF, Flow Cyt (Intra), IHC-P

Platform ID

BAB511043990

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CHD3 antibody [EPNCIR110A]
Cat. No.AB109195
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationWB, ICC/IF, Flow Cyt (Intra), IHC-P
ClonalityMonoclonal
Clone NumberEPNCIR110A
Concentration0.801 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data ATP-dependent helicase that binds and distorts nucleosomal DNA (PubMed : 28977666). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed : 16428440, PubMed : 28977666, PubMed : 30397230, PubMed : 9804427). Involved in transcriptional repression as part of the NuRD complex (PubMed : 27068747). Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity (PubMed : 17626165). See full target information CHD3

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