Anti-CHD4 antibody [EPR22953-38] - ChIP Grade,Abcam,AB240640

What is this antibody validated in? Anti-CHD4 antibody [EPR22953-38] - ChIP Grade (ab240640) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF), ChIP in Human, Mouse samples. What is the molecular weight of CHD4? Anti-CHD4 [EPR22953-38] - ChIP Grade (ab240640) specifically detects a band for CHD4 (UniProt: Q14839) at a molecular weight of 218kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR22953-38] also available for your convenience: ab240640, Carrier free - ab263025 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Human

Application

ChIP, WB, ICC/IF, Flow Cyt (Intra), IP, ChIC/CUT&RUN-seq

Platform ID

BAB011093966

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-CHD4 antibody [EPR22953-38] - ChIP Grade
Cat. No.AB240640
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationChIP, WB, ICC/IF, Flow Cyt (Intra), IP, ChIC/CUT&RUN-seq
ClonalityMonoclonal
Clone NumberEPR22953-38
Concentration0.641 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA (PubMed : 28977666, PubMed : 32543371). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed : 16428440, PubMed : 17626165, PubMed : 28977666, PubMed : 9804427). Localizes to acetylated damaged chromatin in a ZMYND8-dependent manner, to promote transcriptional repression and double-strand break repair by homologous recombination (PubMed : 25593309). Involved in neurogenesis (By similarity). See full target information CHD4

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.