Anti-COX IV antibody [mAbcam33985] - Mitochondrial Marker,Abcam,AB33985
What is this antibody validated in? Anti-COX IV antibody [mAbcam33985] - Mitochondrial Marker (ab33985) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunocytochemistry/immunofluorescence (ICC/IF) in Cow, Human, Mouse, Xenopus laevis samples. What is the molecular weight of COX IV? Anti-COX IV [mAbcam33985] - Mitochondrial Marker (ab33985) specifically detects a band for COX IV (UniProt: P13073) at a molecular weight of 15kDa. Trusted by the scientific community Anti-COX IV [mAbcam33985] - Mitochondrial Marker (ab33985) was first used in a scientific publication in 2007 and has been cited over 120 times in peer-reviewed journals. Reviewed by scientists Anti-COX IV [mAbcam33985] - Mitochondrial Marker (ab33985) has over 25 independent reviews from customers. Other related products We have a range of other formats of antibody clone [mAbcam33985] also available for your convenience: ab33985, HRP - ab62164 , Alexa Fluor® 647 - ab197491 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]
Host
Mouse
Reactivity
Mouse, Cow, Human, Xenopus laevis
Application
WB, ICC/IF, Flow Cyt (Intra)
Platform ID
BAB455359467
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix. See full target information COX4I1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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