Anti-CTGF antibody,Abcam,AB6992
Product Specifications Anti-CTGF antibody (ab6992) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, IP, WB in human, mouse, rat, sheep samples. Anti-CTGF antibody (ab6992) specifically detects CTGF (UniProt ID: P29268; Molecular weight: 35kDa) and is sold in 50 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-CTGF antibody (ab6992) has high sensitivity and specificity. Anti-CTGF antibody (ab6992) has been cited over 313 times in peer reviewed journals and is trusted by the scientific community. Anti-CTGF antibody (ab6992) has 28 independent reviews from customers. Target Information Connective Tissue Growth Factor (CTGF), also known as CCN2 is a protein that regulates various biological process including cell proliferation and migration. CTGF influences the tumor microenvironment by promoting angiogenesis, inflammation, and activation of cancer-associated fibroblasts (CAFs). Elevated levels of CTGF have been observed in several cancers, such as pancreatic, breast, and liver cancers.
Host
Rabbit
Reactivity
Mouse, Rat, Sheep, Human
Application
IHC-FoFr, WB, IHC-Fr, ICC/IF, IP, IHC-P
Platform ID
BAB021389022
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-CTGF antibody
Cat. No.AB6992
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Sheep, Human
ApplicationIHC-FoFr, WB, IHC-Fr, ICC/IF, IP, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Mouse Ccn2 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.5 Preservative: 0.1% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. See full target information CCN2
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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