Anti-CXCR2 antibody [MM0222-7J40],Abcam,AB89254
Host
Mouse
Reactivity
Human
Application
Flow Cyt, WB, FuncS (Neut/Block)
Platform ID
BAB335694405
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-CXCR2 antibody [MM0222-7J40]
Cat. No.AB89254
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationFlow Cyt, WB, FuncS (Neut/Block)
ClonalityMonoclonal
Clone NumberMM0222-7J40
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human CXCR2.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor (PubMed : 1891716). Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed : 8662698). Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. See full target information CXCR2
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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