Anti-CaMKII alpha antibody [6G9],Abcam,AB22609
What is this antibody validated in? Anti-CaMKII alpha antibody [6G9] (ab22609) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr) in Human, Mouse, Rat samples. What is the molecular weight of CaMKII alpha? Anti-CaMKII alpha [6G9] (ab22609) specifically detects a band for CaMKII alpha (UniProt: Q9UQM7) at a molecular weight of 56kDa. Trusted by the scientific community Anti-CaMKII alpha [6G9] (ab22609) was first used in a scientific publication in 2005 and has been cited over 90 times in peer-reviewed journals. Reviewed by scientists Anti-CaMKII alpha [6G9] (ab22609) has over 5 independent reviews from customers. Other related products We have a range of other formats of antibody clone [6G9] also available for your convenience: ab22609, Carrier free - ab187488 , Alexa Fluor® 488 - ab197497 , HRP - ab197500 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]
Host
Mouse
Reactivity
Mouse, Rat, Human
Application
IHC-Fr, WB, IHC-P
Platform ID
BAB863142488
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in various processes, such as synaptic plasticity, neurotransmitter release and long-term potentiation (PubMed : 14722083). Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development (PubMed : 28130356). Also regulates the migration of developing neurons (PubMed : 29100089). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed : 23805378). Phosphorylates the transcription factor ETS1 in response to calcium signaling, thereby decreasing ETS1 affinity for DNA (By similarity). In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (PubMed : 11972023). In response to interferon-beta (IFN-beta) stimulation, stimulates the JAK-STAT signaling pathway (PubMed : 35568036). Acts as a negative regulator of 2-arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity (By similarity). See full target information CAMK2A
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
Please provide the required information below so that we can quickly source your products.