Anti-Calnexin antibody [6F12BE10],Abcam,AB112995

What is this antibody validated in? Anti-Calnexin antibody [6F12BE10] (ab112995) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of Calnexin? Anti-Calnexin [6F12BE10] (ab112995) specifically detects a band for Calnexin (UniProt: P27824) at a molecular weight of 68kDa. Trusted by the scientific community Anti-Calnexin [6F12BE10] (ab112995) was first used in a scientific publication in 2011 and has been cited over 10 times in peer-reviewed journals. Specificity confirmed The specificity of Anti-Calnexin antibody [6F12BE10] (ab112995) has been confirmed by Western blot testing in CANX Knockout HAP1 cells. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Human

Application

Flow Cyt, WB, ICC/IF, IP, IHC-P

Platform ID

BAB299811637

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Calnexin antibody [6F12BE10]
Cat. No.AB112995
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationFlow Cyt, WB, ICC/IF, IP, IHC-P
ClonalityMonoclonal
Clone Number6F12BE10
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityProprietary technique
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.02% Sodium azide Constituents: 99.98% HEPES buffered saline
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. See full target information CANX

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