Anti-Calnexin antibody - C-terminal,Abcam,AB219644

What is this antibody validated in? Anti-Calnexin antibody - C-terminal (ab219644) is a goat polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. What is the molecular weight of Calnexin? Anti-Calnexin - C-terminal (ab219644) specifically detects a band for Calnexin (UniProt: P27824) at a molecular weight of 68kDa.

Host

Goat

Reactivity

Mouse, Human

Application

IHC-P, WB, ICC/IF

Platform ID

BAB174849119

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Calnexin antibody - C-terminal
Cat. No.AB219644
HostGoat
IsotypeIgG
ReactivityMouse, Human
ApplicationIHC-P, WB, ICC/IF
ClonalityPolyclonal
Concentration2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CANX aa 550 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. See full target information CANX

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