Anti-Calnexin antibody - ER Marker,Abcam,AB22595

Anti-Calnexin antibody - ER Marker (ab22595) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IP, WB in human samples. Anti-Calnexin antibody - ER Marker (ab22595) has been cited over 482 times in peer reviewed journals, has been used for calnexin staining and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Calnexin antibody - ER Marker (ab22595) has high sensitivity and specificity. The specificity of Anti-Calnexin antibody - ER Marker (ab22595) has been confirmed by testing in knockout samples. Anti-Calnexin antibody - ER Marker (ab22595) has 28 independent reviews from customers. Anti-Calnexin antibody - ER Marker (ab22595) specifically detects Calnexin (UniProt ID: P27824; Molecular weight: 65kDa) and is sold in 100 µg selling sizes. Calnexin, an endoplasmic reticulum (ER) chaperone protein, plays a crucial role in oncology by influencing the immune response to tumors and cancer cell behavior. It can impair antitumor immunity by inhibiting T-cell infiltration and enhancing PD-1 expression on T cells, which suppresses their activity. Additionally, aberrant O-glycosylation of calnexin is linked to increased cancer cell migration and adhesion. Explore our range of organelle-specific antibodies and dyes and discover why our reagents are deeply trusted by cell biologists.