Anti-Calpain 1 antibody,Abcam,AB155677

Host

Rabbit

Reactivity

Mouse, Human

Application

IP, IHC-P, WB, ICC/IF

Platform ID

BAB799961565

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Calpain 1 antibody
Cat. No.AB155677
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIP, IHC-P, WB, ICC/IF
ClonalityPolyclonal
Concentration0.97 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CAPN1 aa 300-500. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (PubMed : 19617626, PubMed : 21531719, PubMed : 2400579). Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409' (PubMed : 23707407). Cleaves and activates caspase-7 (CASP7) (PubMed : 19617626). See full target information CAPN1

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