Anti-Calpain 1 antibody [CAPN1/1530],Abcam,AB270714

Host

Mouse

Reactivity

Human

Application

IHC-P

Platform ID

BAB049986553

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Calpain 1 antibody [CAPN1/1530]
Cat. No.AB270714
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberCAPN1/1530
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human CAPN1.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (PubMed : 19617626, PubMed : 21531719, PubMed : 2400579). Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409' (PubMed : 23707407). Cleaves and activates caspase-7 (CASP7) (PubMed : 19617626). See full target information CAPN1

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