Anti-Calreticulin antibody [EPR3924] - BSA and Azide free,Abcam,AB271865
What is this antibody validated in? Anti-Calreticulin antibody [EPR3924] - BSA and Azide free (ab271865) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in African green monkey, Human, Mouse samples. What is the molecular weight of Calreticulin? Anti-Calreticulin [EPR3924] - BSA and Azide free (ab271865) specifically detects a band for Calreticulin (UniProt: P27797) at a molecular weight of 48kDa. Specificity confirmed The specificity of Anti-Calreticulin antibody [EPR3924] - BSA and Azide free (ab271865) has been confirmed by Immunocytochemistry/ Immunofluorescence testing in CALR Knockout HAP1 cell line. Other related products We have a range of other formats of antibody clone [EPR3924] also available for your convenience: ab92516 , HRP - ab195511 , Alexa Fluor® 488 - ab196158 , Alexa Fluor® 647 - ab196159 , PE - ab209577 , Alexa Fluor® 405 - ab210431 , Carrier free - ab211962 , Carrier free - ab271865, Alexa Fluor® 555 - ab275117 , Alexa Fluor® 594 - ab275343 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.
Host
Rabbit
Reactivity
Mouse, Human, African green monkey
Application
Flow Cyt (Intra), ICC/IF, WB, IHC-P
Platform ID
BAB425373867
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed : 7876246). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (PubMed : 11149926). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity). See full target information CALR
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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