Anti-Calreticulin antibody [EPR3924] - ER Marker,Abcam,AB92516
Anti-Calreticulin antibody [EPR3924] - ER Marker (ab92516) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, WB in african green monkey, human, mouse, rat samples. Anti-Calreticulin antibody [EPR3924] - ER Marker (ab92516) has been cited over 100 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Calreticulin antibody [EPR3924] - ER Marker (ab92516) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Calreticulin antibody [EPR3924] - ER Marker (ab92516) has been confirmed by testing in knockout samples. Anti-Calreticulin antibody [EPR3924] - ER Marker (ab92516) has 6 independent reviews from customers. Anti-Calreticulin antibody [EPR3924] - ER Marker (ab92516) specifically detects Calreticulin (UniProt ID: P27797; Molecular weight: 46kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR3924 - ab271865 . Antibody clone EPR3924 is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor® 488, Alexa Fluor® 647, PE, Alexa Fluor® 405, Alexa Fluor® 555, Alexa Fluor® 594 ( ab195511 , ab196158 , ab196159 , ab209577 , ab210431 , ab275117 , ab275343 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human, African green monkey
Application
WB, IHC-P, Flow Cyt (Intra), ICC/IF
Platform ID
BAB050386361

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed : 7876246). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (PubMed : 11149926). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity). See full target information CALR
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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