Anti-Calreticulin antibody [FMC 75],Abcam,AB22683
What is this antibody validated in? Anti-Calreticulin antibody [FMC 75] (ab22683) is a mouse monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. Trusted by the scientific community Anti-Calreticulin [FMC 75] (ab22683) was first used in a scientific publication in 2005 and has been cited over 70 times in peer-reviewed journals. Reviewed by scientists Anti-Calreticulin [FMC 75] (ab22683) has over 20 independent reviews from customers.
Host
Mouse
Reactivity
Human
Application
IHC-P, Flow Cyt (Intra), ICC/IF
Platform ID
BAB987905102
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (PubMed : 7876246). Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (PubMed : 11149926). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity). See full target information CALR
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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