Anti-Carbonic anhydrase 2/CA2 antibody [EPR5195],Abcam,AB124687

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human, Rat, Mouse

Application

IHC-P, WB

Platform ID

BAB926523315

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Carbonic anhydrase 2/CA2 antibody [EPR5195]
Cat. No.AB124687
HostRabbit
IsotypeIgG
ReactivityHuman, Rat, Mouse
ApplicationIHC-P, WB
ClonalityMonoclonal
Clone NumberEPR5195
Concentration0.101 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the reversible hydration of carbon dioxide (PubMed : 11327835, PubMed : 11802772, PubMed : 11831900, PubMed : 12056894, PubMed : 12171926, PubMed : 1336460, PubMed : 14736236, PubMed : 15300855, PubMed : 15453828, PubMed : 15667203, PubMed : 15865431, PubMed : 16106378, PubMed : 16214338, PubMed : 16290146, PubMed : 16686544, PubMed : 16759856, PubMed : 16807956, PubMed : 17127057, PubMed : 17251017, PubMed : 17314045, PubMed : 17330962, PubMed : 17346964, PubMed : 17540563, PubMed : 17588751, PubMed : 17705204, PubMed : 18024029, PubMed : 18162396, PubMed : 18266323, PubMed : 18374572, PubMed : 18481843, PubMed : 18618712, PubMed : 18640037, PubMed : 18942852, PubMed : 1909891, PubMed : 1910042, PubMed : 19170619, PubMed : 19186056, PubMed : 19206230, PubMed : 19520834, PubMed : 19778001, PubMed : 7761440, PubMed : 7901850, PubMed : 8218160, PubMed : 8262987, PubMed : 8399159, PubMed : 8451242, PubMed : 8485129, PubMed : 8639494, PubMed : 9265618, PubMed : 9398308). Can also hydrate cyanamide to urea (PubMed : 10550681, PubMed : 11015219). Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (PubMed : 15990874). Essential for bone resorption and osteoclast differentiation (PubMed : 15300855). Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. See full target information CA2

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