Anti-Carboxypeptidase Y antibody [10A5B5],Abcam,AB113685

Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Saccharomyces cerevisiae

Application

WB

Platform ID

BAB051885641

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Carboxypeptidase Y antibody [10A5B5]
Cat. No.AB113685
HostMouse
IsotypeIgG1
ReactivitySaccharomyces cerevisiae
ApplicationWB
ClonalityMonoclonal
Clone Number10A5B5
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityProprietary technique
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.02% Sodium azide Constituents: HEPES buffered saline
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Vacuolar serine-type carboxypeptidase involved in degradation of small peptides (PubMed : 8679540). Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (PubMed : 8679540). Also plays a role in breakdown of the autophagic body and the autophagosome-dependent protein synthesis (PubMed : 29514932). Plays a key role in phytochelatin (PC) synthesis from glutathione (GSH) by cleaving the Gly from GSH and form the PC-peptides of the structure (gamma-Glu-Cys)2-Gly (PubMed : 17408619). Also involved in resistance to xenobiotics via the degradation of glutathione-S-conjugates (PubMed : 19897216). See full target information PRC1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.