Anti-Carboxypeptidase Y antibody,Abcam,AB181691

Target data Vacuolar serine-type carboxypeptidase involved in degradation of small peptides (PubMed : 8679540). Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (PubMed : 8679540). Also plays a role in breakdown of the autophagic body and the autophagosome-dependent protein synthesis (PubMed : 29514932). Plays a key role in phytochelatin (PC) synthesis from glutathione (GSH) by cleaving the Gly from GSH and form the PC-peptides of the structure (gamma-Glu-Cys)2-Gly (PubMed : 17408619). Also involved in resistance to xenobiotics via the degradation of glutathione-S-conjugates (PubMed : 19897216). See full target information PRC1