Anti-Carcino Embryonic Antigen CEA antibody [C66/261] - BSA and Azide free,Abcam,AB212265

Host

Mouse

Reactivity

Human

Application

IHC-P

Platform ID

BAB989404382

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Carcino Embryonic Antigen CEA antibody [C66/261] - BSA and Azide free
Cat. No.AB212265
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberC66/261
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human CEACAM5.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed : 10864933, PubMed : 10910050, PubMed : 2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed : 2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed : 10910050).. (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. See full target information CEACAM5

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