Anti-Casein Kinase 1 alpha antibody [EPR19824],Abcam,AB206652
What is this antibody validated in? Anti-Casein Kinase 1 alpha antibody [EPR19824] (ab206652) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP) in Human, Mouse, Rat samples. What is the molecular weight of Casein Kinase 1 alpha? Anti-Casein Kinase 1 alpha [EPR19824] (ab206652) specifically detects a band for Casein Kinase 1 alpha (UniProt: P48729) at a molecular weight of 39kDa. Trusted by the scientific community Anti-Casein Kinase 1 alpha [EPR19824] (ab206652) was first used in a scientific publication in 2016 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Casein Kinase 1 alpha antibody [EPR19824] (ab206652) has been confirmed by Western blot testing in Casein Kinase 1 alpha Knockout HEK-293T cell line. Other related products We have a range of other formats of antibody clone [EPR19824] also available for your convenience: ab206652, Carrier free - ab223144 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IP, WB
Platform ID
BAB115066564
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (PubMed : 11955436, PubMed : 1409656, PubMed : 18305108, PubMed : 23902688). It can phosphorylate a large number of proteins (PubMed : 11955436, PubMed : 1409656, PubMed : 18305108, PubMed : 23902688). Participates in Wnt signaling (PubMed : 11955436). Phosphorylates CTNNB1 at 'Ser-45' (PubMed : 11955436). May phosphorylate PER1 and PER2 (By similarity). May play a role in segregating chromosomes during mitosis (PubMed : 1409656). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed : 23902688). Acts as a positive regulator of mTORC1 and mTORC2 signaling in response to nutrients by mediating phosphorylation of DEPTOR inhibitor (PubMed : 22017875, PubMed : 22017877). Acts as an inhibitor of NLRP3 inflammasome assembly by mediating phosphorylation of NLRP3 (By similarity). See full target information CSNK1A1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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