Anti-Cathepsin D [EPR3057Y] - Mouse IgG2a (Chimeric),Abcam,AB302649
This mouse monoclonal chimeric antibody has been engineered from a RabMAb parent antibody ( ab75852 ). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed FC-reactive secondary antibodies are recommended. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
IHC-P, WB, ICC/IF, Flow Cyt (Intra)
Platform ID
BAB741378434
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-Cathepsin D [EPR3057Y] - Mouse IgG2a (Chimeric)
Cat. No.AB302649
HostMouse
IsotypeIgG2a
ReactivityHuman, Mouse, Rat
ApplicationIHC-P, WB, ICC/IF, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberEPR3057Y-MsIgG2a
Concentration0.944 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed : 27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. See full target information CTSD
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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