Anti-Cathepsin D antibody,Abcam,AB217310

Host

Rabbit

Reactivity

Rat, Human

Application

IHC-P, ICC/IF, WB

Platform ID

BAB678797223

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cathepsin D antibody
Cat. No.AB217310
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationIHC-P, ICC/IF, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human CTSD aa 100-150 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed : 27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. See full target information CTSD

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