Anti-Cathepsin D antibody [EPR3057Y],Abcam,AB75852

Anti-Cathepsin D antibody [EPR3057Y] (ab75852) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P, IP, WB in human, mouse samples. Anti-Cathepsin D antibody [EPR3057Y] (ab75852) has been cited over 127 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Cathepsin D antibody [EPR3057Y] (ab75852) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Cathepsin D antibody [EPR3057Y] (ab75852) has 11 independent reviews from customers. Anti-Cathepsin D antibody [EPR3057Y] (ab75852) specifically detects Cathepsin D (UniProt ID: P07339; Molecular weight: 38kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR3057Y - ab207549 . Antibody clone EPR3057Y is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 405, PE, APC, HRP, Alkaline Phosphatase ( ab197605 , ab198326 , ab207874 , ab207875 , ab305650 , ab305651 , ab305652 , ab308915 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Species reactivity Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, IHC-P, Flow Cyt (Intra), IP, ICC/IF, IHC-Fr

Platform ID

BAB491353446

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cathepsin D antibody [EPR3057Y]
Cat. No.AB75852
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, IHC-P, Flow Cyt (Intra), IP, ICC/IF, IHC-Fr
ClonalityMonoclonal
Clone NumberEPR3057Y
Concentration0.184 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed : 27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. See full target information CTSD

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.