Anti-Cathepsin D antibody [EPR3057Y] - Chicken IgY (Chimeric),Abcam,AB302646

This chicken monoclonal chimeric antibody has been engineered from RabMab parent antibody ( ab75852 ). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using across absorbed Fc-reactive secondary antibodies are recommended. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Chicken

Reactivity

Human, Mouse, Rat

Application

WB, Flow Cyt (Intra), IHC-P, ICC/IF

Platform ID

BAB116365940

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cathepsin D antibody [EPR3057Y] - Chicken IgY (Chimeric)
Cat. No.AB302646
HostChicken
IsotypeIgY
ReactivityHuman, Mouse, Rat
ApplicationWB, Flow Cyt (Intra), IHC-P, ICC/IF
ClonalityMonoclonal
Clone NumberEPR3057Y-CkIgY
Concentration0.957 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Thiophilic Resin
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed : 27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. See full target information CTSD

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.