Anti-Cathepsin K antibody [3F9],Abcam,AB37259

What is this antibody validated in? Anti-Cathepsin K antibody [3F9] (ab37259) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of Cathepsin K? Anti-Cathepsin K [3F9] (ab37259) specifically detects a band for Cathepsin K (UniProt: P43235) at a molecular weight of 37kDa. Trusted by the scientific community Anti-Cathepsin K [3F9] (ab37259) was first used in a scientific publication in 2006 and has been cited over 30 times in peer-reviewed journals.

Host

Mouse

Reactivity

Mouse, Human

Application

WB, Flow Cyt, IHC-P

Platform ID

BAB116465892

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cathepsin K antibody [3F9]
Cat. No.AB37259
HostMouse
IsotypeIgG2b
ReactivityMouse, Human
ApplicationWB, Flow Cyt, IHC-P
ClonalityMonoclonal
Clone Number3F9
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human CTSK aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS, 0.58% Sodium chloride
Storage-80°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed : 11082042). See full target information CTSK

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