Anti-Cathepsin K antibody [C1],Abcam,AB239506

Host

Mouse

Reactivity

Rat, Human, Pig

Application

WB

Platform ID

BAB741478386

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cathepsin K antibody [C1]
Cat. No.AB239506
HostMouse
IsotypeIgG2b
ReactivityRat, Human, Pig
ApplicationWB
ClonalityMonoclonal
Clone NumberC1
ImmunogenRecombinant Full Length Protein corresponding to Human CTSK.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed : 11082042). See full target information CTSK

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