Anti-Caveolin-2 antibody,Abcam,AB97476

Host

Rabbit

Reactivity

Human, Mouse

Application

IHC-P, IP, WB, ICC/IF

Platform ID

BAB054384441

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Caveolin-2 antibody
Cat. No.AB97476
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationIHC-P, IP, WB, ICC/IF
ClonalityPolyclonal
Concentration0.94 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human CAV2 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity). See full target information CAV2

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