Anti-Caveolin-2 antibody,Abcam,AB2911

Host

Rabbit

Reactivity

Rat, Mouse

Application

WB

Platform ID

BAB741878194

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Caveolin-2 antibody
Cat. No.AB2911
HostRabbit
IsotypeIgG
ReactivityRat, Mouse
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Rat Cav2 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity). See full target information Caveolin-2

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