Anti-Caveolin-3 antibody - Caveolae Marker,Abcam,AB2912

Host

Rabbit

Reactivity

Mouse, Rat, Human, Sheep

Application

ICC, IP, ICC/IF, IHC-P, Flow Cyt, WB, IHC-Fr

Platform ID

BAB866940664

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Caveolin-3 antibody - Caveolae Marker
Cat. No.AB2912
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human, Sheep
ApplicationICC, IP, ICC/IF, IHC-P, Flow Cyt, WB, IHC-Fr
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Cav3 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (PubMed : 19262564). See full target information CAV3

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