Anti-Cdc25B antibody,Abcam,AB167347

Host

Mouse

Reactivity

Human

Application

WB, ICC/IF

Platform ID

BAB757170850

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cdc25B antibody
Cat. No.AB167347
HostMouse
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC/IF
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human CDC25B.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression (PubMed : 1836978, PubMed : 20360007). Directly dephosphorylates CDK1 and stimulates its kinase activity (PubMed : 20360007). Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner (PubMed : 17332740). The three isoforms seem to have a different level of activity (PubMed : 1836978). See full target information CDC25B

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