Anti-Cdc27 antibody [AF3.1],Abcam,AB10538

Host

Mouse

Reactivity

Mouse, Human

Application

Flow Cyt, IHC-P, WB

Platform ID

BAB507245814

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Cdc27 antibody [AF3.1]
Cat. No.AB10538
HostMouse
IsotypeIgG2b
ReactivityMouse, Human
ApplicationFlow Cyt, IHC-P, WB
ClonalityMonoclonal
Clone NumberAF3.1
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human CDC27 aa 800 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed : 18485873). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins : it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (PubMed : 18485873). The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins (PubMed : 29033132). See full target information CDC27

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.