Anti-Clathrin heavy chain antibody,Abcam,AB21679
What is this antibody validated in? Anti-Clathrin heavy chain antibody (ab21679) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Clathrin heavy chain? Anti-Clathrin heavy chain (ab21679) specifically detects a band for Clathrin heavy chain (UniProt: Q00610) at a molecular weight of 180kDa. Trusted by the scientific community Anti-Clathrin heavy chain (ab21679) was first used in a scientific publication in 2006 and has been cited over 140 times in peer-reviewed journals. Reviewed by scientists Anti-Clathrin heavy chain (ab21679) has over 35 independent reviews from customers.
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
ICC/IF, WB
Platform ID
BAB138355380
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed : 15858577, PubMed : 16968737, PubMed : 21297582). The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed : 23532825). Plays a role in early autophagosome formation (PubMed : 20639872). Interaction with DNAJC6 mediates the recruitment of HSPA8 to the clathrin lattice and creates local destabilization of the lattice promoting uncoating (By similarity). See full target information CLTC
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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