Anti-Claudin 15 antibody,Abcam,AB238820

Host

Rabbit

Reactivity

Human

Application

ICC/IF, IHC-P

Platform ID

BAB576024049

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Claudin 15 antibody
Cat. No.AB238820
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human Claudin-15 aa 50-150. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Forms paracellular channels : polymerizes in tight junction strands with cation- and water-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability (PubMed : 12055082, PubMed : 13129853, PubMed : 31188544, PubMed : 35650657, PubMed : 36008380). In intestinal epithelium, allows for sodium and water fluxes from the peritoneal side to the lumen of the intestine to regulate nutrient absorption and intestinal morphogenesis (By similarity). See full target information Claudin-15

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