Anti-Claudin 4 antibody [EPRR17575],Abcam,AB210796

What is this antibody validated in? Anti-Claudin 4 antibody [EPRR17575] (ab210796) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of Claudin 4? Anti-Claudin 4 [EPRR17575] (ab210796) specifically detects a band for Claudin 4 (UniProt: O14493) at a molecular weight of 22kDa. Trusted by the scientific community Anti-Claudin 4 [EPRR17575] (ab210796) was first used in a scientific publication in 2016 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Claudin 4 antibody [EPRR17575] (ab210796) has been confirmed by Western blot testing in CLDN4 Knockout MCF7 cells. Other related products We have a range of other formats of antibody clone [EPRR17575] also available for your convenience: ab210796, Carrier free - ab240384 , Alexa Fluor® 488 - ab311027 , Alexa Fluor® 647 - ab311153 , Alexa Fluor® 594 - ab311799 , Alexa Fluor® 568 - ab313082 , Alexa Fluor® 555 - ab313276 , Alexa Fluor® 750 - ab321368 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human, Mouse

Application

IP, IHC-P, WB

Platform ID

BAB201136495

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Claudin 4 antibody [EPRR17575]
Cat. No.AB210796
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationIP, IHC-P, WB
ClonalityMonoclonal
Clone NumberEPRR17575
Concentration0.452 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Can associate with other claudins to regulate tight junction structural and functional strand dynamics (PubMed : 35773259, PubMed : 36008380). May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts (By similarity) (PubMed : 36008380). May integrate into CLDN3 strands to modulate localized tight junction barrier properties (PubMed : 35773259, PubMed : 36008380). May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance (PubMed : 35773259, PubMed : 36008380). Cannot form tight junction strands on its own (PubMed : 35773259, PubMed : 36008380). See full target information CLDN4

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