Anti-Claudin18 antibody [43-14A],Abcam,AB314690

Product Specifications Anti-Claudin18 antibody [43-14A] (ab314690) is a mouse recombinant monoclonal antibody and is validated for use in in human samples. Anti-Claudin18 antibody [43-14A] (ab314690) specifically detects Claudin18 (UniProt ID: P56856; Molecular weight: 28kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (50 µL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Claudin18 antibody [43-14A] (ab314690) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Related Products Conjugation-ready, carrier free format available for antibody clone 43-14A - ab314691 . Target Information Claudin-18 is a protein encoded by the CLDN18 gene. It belongs to the claudin family, which forms tight junction strands in epithelial cells. Claudin-18 plays a crucial role in maintaining the integrity of these cell junctions, which are essential for various physiological processes. Disruption of these junctions can lead to increased cancer invasiveness and metastasis. Claudin 18 is a key marker in oncology due to its role in cancer progression. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]