Anti-Cofilin antibody - Loading Control,Abcam,AB42824
What is this antibody validated in? Anti-Cofilin antibody (ab42824) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Cofilin-1? Anti-Cofilin (ab42824) specifically detects a band for Cofilin-1 (UniProt: P23528) at a molecular weight of 19kDa. Trusted by the scientific community Anti-Cofilin (ab42824) was first used in a scientific publication in 2007 and has been cited over 80 times in peer-reviewed journals. Reviewed by scientists Anti-Cofilin (ab42824) has over 5 independent reviews from customers.
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IHC-P, ICC/IF, WB
Platform ID
BAB265816698
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed : 11812157). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed : 15580268). Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (PubMed : 21834987). Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed : 23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity). See full target information CFL1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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