Anti-Collagen I antibody [EPR7785],Abcam,AB138492

Anti-Collagen I antibody [EPR7785] (ab138492) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-Fr IHC-P and WB. Anti-Collagen I antibody [EPR7785] (ab138492) was first used in a scientific publication in 2014 and has been cited over 253 times in peer reviewed journals. It's performance in Western Blot and IHC in human samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Collagen I antibody [EPR7785] (ab138492) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Collagen I antibody [EPR7785] (ab138492) has been confirmed by testing in Collagen I knockout cells. Anti-Collagen I antibody [EPR7785] (ab138492) has 34 independent reviews from customers. Anti-Collagen I antibody [EPR7785] (ab138492) specifically detects Collagen I (UniProt ID: P02452; Molecular weight: 95kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR7785 - ab215969 . Antibody clone EPR7785 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, Alexa Fluor ® 594, Alexa Fluor ® 568, Alexa Fluor ® 555, Alexa Fluor ® 750 ( ab275996 , ab280968 , ab311739 , ab313018 , ab313221 , ab321114 ). Collagen I modulates the tumor microenvironment by enhancing tissue rigidity and facilitating neoplastic cell proliferation. Additionally, it contributes to immune evasion by forming a structural barrier that impedes T-cell infiltration and activity. Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

ICC/IF, IHC-P, IHC-Fr, WB

Platform ID

BAB578822705

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Collagen I antibody [EPR7785]
Cat. No.AB138492
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, IHC-P, IHC-Fr, WB
ClonalityMonoclonal
Clone NumberEPR7785
Concentration0.964 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Type I collagen is a member of group I collagen (fibrillar forming collagen). See full target information COL1A1

Category Paths

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