Anti-Collagen IV antibody,Abcam,AB19808

What is this antibody validated in? Anti-Collagen IV antibody (ab19808) is a rabbit polyclonal antibody and is validated for use in Immunohistochemistry (IHC-P) in Mouse samples. Trusted by the scientific community Anti-Collagen IV (ab19808) was first used in a scientific publication in 2005 and has been cited over 160 times in peer-reviewed journals. Reviewed by scientists Anti-Collagen IV (ab19808) has over 20 independent reviews from customers.

Host

Rabbit

Reactivity

Mouse

Application

IHC-P

Platform ID

BAB078972633

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Collagen IV antibody
Cat. No.AB19808
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationIHC-P
ClonalityPolyclonal
Concentration3.75 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Mouse Col4a1.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. See full target information Col4a1 Additional targets ,Collagen alpha-2(IV) chain,Col4a4

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