Anti-Collagen Type IV alpha 3 (COL4a3) antibody,Abcam,AB111742

Host

Rabbit

Reactivity

Human, African green monkey

Application

ICC/IF, IHC-P

Platform ID

BAB141553844

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Collagen Type IV alpha 3 (COL4a3) antibody
Cat. No.AB111742
HostRabbit
IsotypeIgG
ReactivityHuman, African green monkey
ApplicationICC/IF, IHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human Collagen alpha-3(IV) chain. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms. See full target information Collagen alpha-3(IV) chain

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.