Anti-Collagen Type IV alpha 3 (COL4a3) antibody,Abcam,AB223227
Host
Goat
Reactivity
Human
Application
IHC-P
Platform ID
BAB454060091
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-Collagen Type IV alpha 3 (COL4a3) antibody
Cat. No.AB223227
HostGoat
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human Collagen alpha-3(IV) chain aa 300-400. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms. See full target information Collagen alpha-3(IV) chain
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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