Anti-Connexin 43 / GJA1 (phospho S368) antibody,Abcam,AB30559

Target data Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity : acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization (PubMed : 15181016). Plays an essential role in gap junction communication in the ventricles (By similarity). See full target information Gja1 phospho S368