Anti-Corin antibody,Abcam,AB232807

Host

Rabbit

Reactivity

Rat

Application

WB, IHC-P

Platform ID

BAB892528376

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Corin antibody
Cat. No.AB232807
HostRabbit
IsotypeIgG
ReactivityRat
ApplicationWB, IHC-P
ClonalityPolyclonal
ImmunogenRecombinant Fragment Protein within Rat Corin aa 500-650. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Serine-type endopeptidase involved in atrial natriuretic peptide (NPPA) processing (PubMed : 17660514). Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation (By similarity). Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus (By similarity). Also acts as a regulator of sodium reabsorption in kidney (PubMed : 20613715). May also process pro-NPPB the B-type natriuretic peptide (By similarity). See full target information Corin

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