Anti-Corin antibody [EPR22613-21],Abcam,AB255812

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat

Application

IHC-P, IHC-Fr

Platform ID

BAB517540870

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Corin antibody [EPR22613-21]
Cat. No.AB255812
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationIHC-P, IHC-Fr
ClonalityMonoclonal
Clone NumberEPR22613-21
Concentration0.537 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Serine-type endopeptidase involved in atrial natriuretic peptide (NPPA) processing (PubMed : 11884416, PubMed : 15637153). Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation (PubMed : 11884416, PubMed : 15637153, PubMed : 22418978). Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus (PubMed : 22437503). Also acts as a regulator of sodium reabsorption in kidney (PubMed : 20613715, PubMed : 22418978). May also process pro-NPPB the B-type natriuretic peptide (By similarity). See full target information Corin

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.