Anti-Cortactin antibody [EP1922Y],Abcam,AB81208
What is this antibody validated in? Anti-Cortactin antibody [EP1922Y] (ab81208) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. What is the molecular weight of Cortactin? Anti-Cortactin [EP1922Y] (ab81208) specifically detects a band for Cortactin (UniProt: Q14247) at a molecular weight of 62kDa. Trusted by the scientific community Anti-Cortactin [EP1922Y] (ab81208) was first used in a scientific publication in 2009 and has been cited over 30 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Cortactin antibody [EP1922Y] (ab81208) has been confirmed by Western blot testing in CTTN Knockout HAP1 cell line, ab266819 . Other related products We have a range of other formats of antibody clone [EP1922Y] also available for your convenience: ab81208, Alexa Fluor® 488 - ab202648 , Alexa Fluor® 647 - ab202650 , PE - ab209758 , Alexa Fluor® 555 - ab215298 , Alexa Fluor® 594 - ab215300 , Carrier free - ab223125 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Human
Application
ICC/IF, WB, IHC-P, IP, Flow Cyt (Intra)
Platform ID
BAB955209539
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Contributes to the organization of the actin cytoskeleton and cell shape (PubMed : 21296879). Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed : 20861316). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (PubMed : 17959782). Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity). Required for stabilization of KCNH1 channels at the cell membrane (PubMed : 23144454). Plays a role in the invasiveness of cancer cells, and the formation of metastases (PubMed : 16636290). See full target information CTTN
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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- Products>Primary Antibodies>Recombinant Antibodies
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