Anti-Ctip1/BCL-11A antibody [EPR14943-44],Abcam,AB191401

What is this antibody validated in? Anti-Ctip1/BCL-11A antibody [EPR14943-44] (ab191401) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) and ChIC/CUT&RUN sequencing in Human, Rat samples. What is the molecular weight of Ctip1/BCL-11A? Anti-Ctip1/BCL-11A [EPR14943-44] (ab191401) specifically detects a band for Ctip1/BCL-11A (UniProt: Q9H165) at a molecular weight of 91kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Ctip1/BCL-11A antibody [EPR14943-44] (ab191401) has been confirmed by Western blot testing in BCL11A Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [EPR14943-44] also available for your convenience: ab191401, Carrier free - ab242406 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Rat, Human

Application

WB, Flow Cyt (Intra), IHC-P, IP, ICC/IF, ChIC/CUT&RUN-seq

Platform ID

BAB771563938

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Ctip1/BCL-11A antibody [EPR14943-44]
Cat. No.AB191401
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationWB, Flow Cyt (Intra), IHC-P, IP, ICC/IF, ChIC/CUT&RUN-seq
ClonalityMonoclonal
Clone NumberEPR14943-44
Concentration0.94 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor (PubMed : 16704730, PubMed : 29606353). Associated with the BAF SWI/SNF chromatin remodeling complex (PubMed : 23644491, PubMed : 39607926). Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene (PubMed : 29606353, PubMed : 39423807). Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1; hence indirectly repressing fetal hemoglobin (HbF) level (PubMed : 26375765, PubMed : 29606353, PubMed : 39423807, PubMed : 39607926). Involved in brain development (PubMed : 27453576). May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity). May function as a modulator of the transcriptional repression activity of NR2F2 (By similarity). See full target information BCL11A

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