Anti-Cyclophilin E antibody [EPR10805(B)],Abcam,AB154865

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

WB

Platform ID

BAB649400076

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Cyclophilin E antibody [EPR10805(B)]
Cat. No.AB154865
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityMonoclonal
Clone NumberEPR10805(B)
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Involved in pre-mRNA splicing as component of the spliceosome (PubMed : 11991638, PubMed : 28076346). Combines RNA-binding and PPIase activities (PubMed : 18258190, PubMed : 20460131, PubMed : 20677832, PubMed : 8977107). Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules (PubMed : 18258190, PubMed : 20460131, PubMed : 8977107). Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins (PubMed : 18258190, PubMed : 20541251, PubMed : 20677832, PubMed : 8977107). Inhibits KMT2A activity; this requires proline isomerase activity (PubMed : 20460131, PubMed : 20541251, PubMed : 20677832). See full target information PPIE

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