Anti-Cytochrome C antibody [7H8.2C12],Abcam,AB13575
What is this antibody validated in? Anti-Cytochrome C antibody [7H8.2C12] (ab13575) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of Cytochrome C? Anti-Cytochrome C [7H8.2C12] (ab13575) specifically detects a band for Cytochrome C (UniProt: P99999) at a molecular weight of 12kDa. Trusted by the scientific community Anti-Cytochrome C [7H8.2C12] (ab13575) was first used in a scientific publication in 2004 and has been cited over 200 times in peer-reviewed journals. Reviewed by scientists Anti-Cytochrome C [7H8.2C12] (ab13575) has over 30 independent reviews from customers. Other related products We have a range of other formats of antibody clone [7H8.2C12] also available for your convenience: ab13575, HRP - ab199222 , Carrier free - ab237966 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]
Host
Mouse
Reactivity
Human
Application
Flow Cyt (Intra), ICC/IF, IHC-P, WB
Platform ID
BAB775462066
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. See full target information CYCS
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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