Anti-Cytochrome C antibody [EPR1327],Abcam,AB133504
What is this antibody validated in? Anti-Cytochrome C antibody [EPR1327] (ab133504) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Cytochrome C? Anti-Cytochrome C [EPR1327] (ab133504) specifically detects a band for Cytochrome C (UniProt: P99999) at a molecular weight of 11kDa. Trusted by the scientific community Anti-Cytochrome C [EPR1327] (ab133504) was first used in a scientific publication in 2012 and has been cited over 230 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR1327] also available for your convenience: ab133504, Alexa Fluor® 488 - ab192485 , Alexa Fluor® 647 - ab192486 , HRP - ab193239 , Carrier free - ab218312 , PE - ab317900 , APC - ab317940 , Alexa Fluor® 594 - ab318022 , Alexa Fluor® 555 - ab318064 , Alexa Fluor® 750 - ab321049 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB, IHC-P, ICC/IF, IP
Platform ID
BAB275512042
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. See full target information CYCS
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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