Anti-Cytokeratin 10 + 13 antibody [DE-K13],Abcam,AB9383

Host

Mouse

Reactivity

Zebrafish

Application

IHC-Fr

Platform ID

BAB463455579

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cytokeratin 10 + 13 antibody [DE-K13]
Cat. No.AB9383
HostMouse
IsotypeIgG2a
ReactivityZebrafish
ApplicationIHC-Fr
ClonalityMonoclonal
Clone NumberDE-K13
Concentration1 mg/mL Batch dependent concentration
ImmunogenFull Length Protein corresponding to Human KRT10. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.09% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity).. (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur. See full target information KRT10 Additional targets Keratin, type I cytoskeletal 13

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